Application
QPCT Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the QPCT antibody detected the QPCT protein (arrow).| Product Name | QPCT Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | QPCT Glutaminyl-peptide cyclotransferase Glutaminyl cyclase Glutaminyl-tRNA cyclotransferase Glutamyl cyclase |
|---|---|
| Molecular Weight(MW) | 40877 Da |
| Function | Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-beta-amyloid. May be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides |
| Tissue Specificity | This QPCT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 314-343 amino acids from the C-terminal region of human QPCT. |
| Cellular Localization | Secreted. |
| Entrez Gene | 25797 |
|---|---|
| Nucleotide Accession | NP_036545.1 |
Application
QPCT Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the QPCT antibody detected the QPCT protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
