Application
RAB11FIP2 Antibody (Center) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the RAB11FIP2 antibody detected the RAB11FIP2 protein (arrow).Application
RAB11FIP2 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the RAB11FIP2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.Application
RAB11FIP2 Antibody (Center) flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | RAB11FIP2 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RAB11FIP2; KIAA0941; Rab11 family-interacting protein 2; NRip11 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA0941 |
|---|---|
| Alternative Names | RAB11FIP2 KIAA0941 Rab11 family-interacting protein 2 NRip11 |
| Molecular Weight(MW) | 58279 Da |
| Function | A Rab11 effector protein acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Binds preferentially to phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA). Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity |
| Tissue Specificity | This RAB11FIP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 352-382 amino acids from the Central region of human RAB11FIP2. |
| Cellular Localization | Cell membrane; Peripheral membrane protein. Recycling endosome membrane; Peripheral membrane protein Note=Translocates with RAB11A from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane |
| Entrez Gene | 22841 |
|---|---|
| Nucleotide Accession | NP_055719.1 |
Application
RAB11FIP2 Antibody (Center) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the RAB11FIP2 antibody detected the RAB11FIP2 protein (arrow).
Application
RAB11FIP2 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the RAB11FIP2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
RAB11FIP2 Antibody (Center) flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
