Application
RAB12 Antibody (N-term) western blot analysis in mouse cerebellum tissue and mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the RAB12 antibody detected the RAB12 protein (arrow).| Product Name | RAB12 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RAB12; Ras-related protein Rab-12 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | RAB12 Ras-related protein Rab-12 |
|---|---|
| Molecular Weight(MW) | 27248 Da |
| Function | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor (By similarity) |
| Tissue Specificity | This RAB12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-100 amino acids from the N-terminal region of human RAB12. |
| Cellular Localization | Recycling endosome membrane; Lipid-anchor; Cytoplasmic side (By similarity). Lysosome membrane; Lipid-anchor; Cytoplasmic side (By similarity). Golgi apparatus membrane (By similarity) |
| Entrez Gene | 201475 |
|---|---|
| Nucleotide Accession | NP_001020471.2 |
Application
RAB12 Antibody (N-term) western blot analysis in mouse cerebellum tissue and mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the RAB12 antibody detected the RAB12 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
