RAB22A Antibody (C-term) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the RAB22A antibody detected the RAB22A protein (arrow).
Plays a role in endocytosis and intracellular protein transport. Mediates trafficking of TF from early endosomes to recycling endosomes. Required for NGF-mediated endocytosis of NTRK1, and subsequent neurite outgrowth. Binds GTP and GDP and has low GTPase activity. Alternates between a GTP-bound active form and a GDP-bound inactive form
Tissue Specificity
This RAB22A antibody is generated from rabbits immunized with a KLH conjugated synthetic between 165-192 amino acids selected from the C-terminal region of human RAB22A.
Cellular Localization
Endosome membrane; Lipid-anchor (By similarity). Cell membrane; Lipid-anchor (By similarity). Early endosome. Cell projection, ruffle. Cytoplasmic vesicle Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side (By similarity) Note=Recruited to phagosomes containing S.aureus or M.tuberculosis
RAB22A Antibody (C-term) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the RAB22A antibody detected the RAB22A protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.