RAB26 Antibody (C-term) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the RAB26 antibody detected the RAB26 protein (arrow).
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Mediates transport of ADRA2A and ADRA2B from the Golgi to the cell membrane. Plays a role in the maturation of zymogenic granules and in pepsinogen secretion in the stomach Plays a role in the secretion of amylase from acinar granules in the parotid gland
Tissue Specificity
Predominantly expressed in brain.
Cellular Localization
Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesicle, secretory vesicle membrane; Lipid-anchor; Cytoplasmic side (Probable). Note=Not localized at the plasma membrane (By similarity). Inhibition of S- geranylgeranyl cysteine formation abolishes membrane location
RAB26 Antibody (C-term) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the RAB26 antibody detected the RAB26 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.