Application
RAB27A Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the RAB27A antibody detected the RAB27A protein (arrow).| Product Name | RAB27A Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RAB27A; RAB27; Ras-related protein Rab-27A; GTP-binding protein Ram |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | RAB27 |
|---|---|
| Alternative Names | RAB27A RAB27 Ras-related protein Rab-27A GTP-binding protein Ram |
| Molecular Weight(MW) | 24868 Da |
| Function | Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse |
| Tissue Specificity | Found in all the examined tissues except in brain. Low expression was found in thymus, kidney, muscle and placenta. Detected in melanocytes, and in most tumor cell lines examined. Expressed in cytotoxic T-lymphocytes (CTL) and mast cells |
| Cellular Localization | Membrane; Lipid-anchor. Melanosome. Late endosome. Lysosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Localizes to endosomal exocytic vesicles |
| Entrez Gene | 5873 |
|---|---|
| Nucleotide Accession | NP_004571.2 |
Application
RAB27A Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the RAB27A antibody detected the RAB27A protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Data sheet for OM219234