Application
RAB3GAP1 Antibody (Center) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the RAB3GAP1 antibody detected the RAB3GAP1 protein (arrow).Application
RAB3GAP1 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of the RAB3GAP1 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.Application
RAB3GAP1 Antibody (Center) flow cytometric analysis of MCF-7 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | RAB3GAP1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RAB3GAP1; KIAA0066; RAB3GAP; Rab3 GTPase-activating protein catalytic subunit; RAB3 GTPase-activating protein 130 kDa subunit; Rab3-GAP p130 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA0066 RAB3GAP |
|---|---|
| Alternative Names | RAB3GAP1 KIAA0066 RAB3GAP Rab3 GTPase-activating protein catalytic subunit RAB3 GTPase-activating protein 130 kDa subunit Rab3-GAP p130 |
| Molecular Weight(MW) | 110524 Da |
| Function | Probable catalytic subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Specifically converts active Rab3-GTP to the inactive form Rab3-GDP. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters |
| Tissue Specificity | Ubiquitous. |
| Cellular Localization | Cytoplasm. Note=In neurons, it is enriched in the synaptic soluble fraction |
| Entrez Gene | 22930 |
|---|---|
| Nucleotide Accession | NP_036365.1 |
Application
RAB3GAP1 Antibody (Center) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the RAB3GAP1 antibody detected the RAB3GAP1 protein (arrow).
Application
RAB3GAP1 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of the RAB3GAP1 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
RAB3GAP1 Antibody (Center) flow cytometric analysis of MCF-7 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
