RAC3 Antibody (Center) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the RAC3 antibody detected the RAC3 protein (arrow).
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as cell spreading and the formation of actin-based protusions including lamellipodia and membrane ruffles
Tissue Specificity
Highest levels in brain, also detected in heart, placenta and pancreas
Cellular Localization
Cytoplasm. Endomembrane system. Cell projection, lamellipodium. Note=Membrane-associated when activated. Co-localizes with NRBP to endomembranes and at the cell periphery in lamellipodia
RAC3 Antibody (Center) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the RAC3 antibody detected the RAC3 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.