Application
RALBP1 Antibody (Center) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the RALBP1 antibody detected the RALBP1 protein (arrow).Application
RALBP1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RALBP1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | RALBP1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RALBP1; RLIP1; RLIP76; RalA-binding protein 1; 76 kDa Ral-interacting protein; Dinitrophenyl S-glutathione ATPase; Ral-interacting protein 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | RLIP1 RLIP76 |
|---|---|
| Alternative Names | RALBP1 RLIP1 RLIP76 RalA-binding protein 1 76 kDa Ral-interacting protein Dinitrophenyl S-glutathione ATPase Ral-interacting protein 1 |
| Molecular Weight(MW) | 76063 Da |
| Function | Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin |
| Tissue Specificity | Expressed ubiquitously but at low levels. Shows a strong expression in the erythrocytes |
| Cellular Localization | Membrane; Peripheral membrane protein. |
| Entrez Gene | 10928 |
|---|---|
| Nucleotide Accession | NP_006779.1 |
Application
RALBP1 Antibody (Center) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the RALBP1 antibody detected the RALBP1 protein (arrow).
Application
RALBP1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RALBP1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
