Application
RAP1B Antibody (C-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the RAP1B antibody detected the RAP1B protein (arrow).| Product Name | RAP1B Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RAP1B; Ras-related protein Rap-1b; GTP-binding protein smg p21B |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | RAP1B Ras-related protein Rap-1b GTP-binding protein smg p21B |
|---|---|
| Molecular Weight(MW) | 20825 Da |
| Function | GTP-binding protein that possesses intrinsic GTPase activity. Contributes to the polarizing activity of KRIT1 and CDH5 in the establishment and maintenance of correct endothelial cell polarity and vascular lumen. Required for the localization of phosphorylated PRKCZ, PARD3 and TIAM1 to the cell junction |
| Tissue Specificity | This RAP1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 149-178 amino acids from the C-terminal region of human RAP1B. |
| Cellular Localization | Cell membrane. Cytoplasm, cytosol. Cell junction. Note=May shuttle between plasma membrane and cytosol Presence of KRIT1 and CDH5 is required for its localization to the cell junction |
| Entrez Gene | 5908 |
|---|---|
| Nucleotide Accession | NP_056461.1 NP_001010942.1 |
Application
RAP1B Antibody (C-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the RAP1B antibody detected the RAP1B protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
