Application
RASA4 Antibody (N-term) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the RASA4 antibody detected the RASA4 protein (arrow).| Product Name | RASA4 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CAPRI, GAPL, KIAA0538 |
|---|---|
| Alternative Names | RASA4 CAPRI GAPL KIAA0538 Ras GTPase-activating protein 4 Calcium-promoted Ras inactivator Ras p21 protein activator 4 RasGAP-activating-like protein 2 |
| Molecular Weight(MW) | 90458 Da |
| Function | Ca(2+)-dependent Ras GTPase-activating protein, that switches off the Ras-MAPK pathway following a stimulus that elevates intracellular calcium. Functions as an adaptor for Cdc42 and Rac1 during FcR-mediated phagocytosis |
| Tissue Specificity | Widely expressed. |
| Cellular Localization | Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein. Note=Localized to the cytosol as a result of its lack of phosphoinositide binding activity. Upon agonist-stimulated calcium mobilization, utilizes the C2A and C2B domains to associate with the plasma membrane |
| Entrez Gene | 10156 |
|---|---|
| Nucleotide Accession | NP_008920.5 |
Application
RASA4 Antibody (N-term) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the RASA4 antibody detected the RASA4 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
