Application
RASSF7 Antibody (C-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the RASSF7 antibody detected the RASSF7 protein (arrow).| Product Name | RASSF7 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RASSF7; C11orf13; HRC1; Ras association domain-containing protein 7; HRAS1-related cluster protein 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | C11orf13 HRC1 |
|---|---|
| Alternative Names | RASSF7 C11orf13 HRC1 Ras association domain-containing protein 7 HRAS1-related cluster protein 1 |
| Molecular Weight(MW) | 39945 Da |
| Function | Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti- apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization |
| Tissue Specificity | This RASSF7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325-354 amino acids from the C-terminal region of human RASSF7. |
| Cellular Localization | Cytoplasm, cytoskeleton, centrosome. Note=Colocalizes with gamma-tubulin |
| Entrez Gene | 8045 |
|---|---|
| Nucleotide Accession | NP_001137466.1 NP_003466.1 NP_001137465.1 |
Application
RASSF7 Antibody (C-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the RASSF7 antibody detected the RASSF7 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
