Application
RASSF10 Antibody (Center) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the RASSF10 antibody detected the RASSF10 protein (arrow).Application
RASSF10 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RASSF10 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | RASSF10 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RASSF10; Ras association domain-containing protein 10 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | RASSF10 Ras association domain-containing protein 10 |
|---|---|
| Molecular Weight(MW) | 56900 Da |
| Tissue Specificity | Expressed in brain. Tends to be down-regulated in astrocytic gliomas due to promoter methylation. Methylation occurs early in gliomagenesis and the extent of methylation parallels with higher glioma grades, so that methylation is observed in close to 70% WHO grade IV primary glioblastomas, but not in grade I astrocytomas |
| Cellular Localization | Cytoplasm, cytosol. Cytoplasm, cytoskeleton, centrosome. Cytoplasm, cytoskeleton, spindle pole. Note=During interphase, predominantly cytoplasmic, although some nuclear staining in several tumor cell contexts. During prophase, observed at developing centrosomes. Displays persistent localization with centrosomally radiating microtubule bundles until late telophase Associates with spindle poles particularly during metaphase and anaphase before relocating back to the cytoplasm |
| Entrez Gene | 644943 |
|---|---|
| Nucleotide Accession | NP_001073990.2 |
Application
RASSF10 Antibody (Center) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the RASSF10 antibody detected the RASSF10 protein (arrow).
Application
RASSF10 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RASSF10 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
