Application
rat BAD Antibody (Center S109) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the BAD antibody detected the BAD protein (arrow).| Product Name | Rat BAD Antibody (Center S109) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | Bad Bcl2 antagonist of cell death Bcl-2-binding component 6 Bcl-xL/Bcl-2-associated death promoter |
|---|---|
| Molecular Weight(MW) | 22228 Da |
| Function | Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways |
| Tissue Specificity | Expressed in all tissues tested, including brain, liver, spleen and heart. In the brain, restricted to epithelial cells of the choroid plexus. Isoform alpha is the more abundant form |
| Cellular Localization | Mitochondrion outer membrane (By similarity). Cytoplasm (By similarity). Note=Upon phosphorylation, locates to the cytoplasm (By similarity) |
| Entrez Gene | 64639 |
|---|---|
| Nucleotide Accession | NP_073189.1 |
Application
rat BAD Antibody (Center S109) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the BAD antibody detected the BAD protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
