Application
RARB Antibody (N-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the RARB antibody detected the RARB protein (arrow).| Product Name | RA_ Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | HAP, NR1B2 |
|---|---|
| Alternative Names | RARB HAP NR1B2 Retinoic acid receptor beta HBV-activated protein Nuclear receptor subfamily 1 group B member 2 RAR-epsilon |
| Molecular Weight(MW) | 50489 Da |
| Function | Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function |
| Tissue Specificity | This RARB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2-31 amino acids from the N-terminal region of human RARB. |
| Cellular Localization | Isoform Beta-1: Nucleus. Isoform Beta-4: Cytoplasm. |
| Entrez Gene | 5915 |
|---|---|
| Nucleotide Accession | NP_057236.1 NP_000956.2 |
Application
RARB Antibody (N-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the RARB antibody detected the RARB protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
