Application
RBBP7 Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the RBBP7 antibody detected the RBBP7 protein (arrow).Application
Western blot analysis of RBBP7 (arrow) using rabbit polyclonal RBBP7 Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the RBBP7 gene.| Product Name | RBBP7 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RBBP7; RBAP46; Histone-binding protein RBBP7; Histone acetyltransferase type B subunit 2; Nucleosome-remodeling factor subunit RBAP46; Retinoblastoma-binding protein 7; Retinoblastoma-binding protein p46 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | RBAP46 |
|---|---|
| Alternative Names | RBBP7 RBAP46 Histone-binding protein RBBP7 Histone acetyltransferase type B subunit 2 Nucleosome-remodeling factor subunit RBAP46 Retinoblastoma-binding protein 7 Retinoblastoma-binding protein p46 |
| Molecular Weight(MW) | 47820 Da |
| Function | Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assembly following DNA replication; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; and the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex |
| Tissue Specificity | This RBBP7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 190-219 amino acids from the Central region of human RBBP7. |
| Cellular Localization | Nucleus. |
| Entrez Gene | 5931 |
|---|---|
| Nucleotide Accession | NP_002884.1 |
Application
RBBP7 Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the RBBP7 antibody detected the RBBP7 protein (arrow).
Application
Western blot analysis of RBBP7 (arrow) using rabbit polyclonal RBBP7 Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the RBBP7 gene.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
