RBM11 Antibody (N-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the RBM11 antibody detected the RBM11 protein (arrow).
RBM11; Splicing regulator RBM11; RNA-binding motif protein 11
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Alternative Names
RBM11 Splicing regulator RBM11 RNA-binding motif protein 11
Molecular Weight(MW)
32179 Da
Function
Tissue-specific splicing factor with potential implication in the regulation of alternative splicing during neuron and germ cell differentiation. Antagonizes SRSF1-mediated BCL-X splicing. May affect the choice of alternative 5' splice sites by binding to specific sequences in exons and antagonizing the SR protein SRSF1
Tissue Specificity
Expressed in brain, hippocampus, prefrontal cortex, cerebellum, spinal cord, testis, mammary gland, spleen and kidney. Also expressed in fetal brain
Cellular Localization
Nucleus, nucleoplasm. Nucleus speckle. Note=Enriched in SRSF2-containing splicing speckles; shuttles between nucleoplasm and speckles
RBM11 Antibody (N-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the RBM11 antibody detected the RBM11 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.