Application
RBPMS Antibody (C-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the RBPMS antibody detected the RBPMS protein (arrow).| Product Name | RBPMS Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RBPMS;HERMES; RNA-binding protein with multiple splicing; RNA-binding protein with multiple splicing; Heart and RRM expressed sequence |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | HERMES |
|---|---|
| Alternative Names | RBPMS HERMES RNA-binding protein with multiple splicing RNA-binding protein with multiple splicing Heart and RRM expressed sequence |
| Molecular Weight(MW) | 21802 Da |
| Function | Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C- terminal SSXS motif, possibly through recruitment of TGFBR1 Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins. Binds to poly(A) RNA |
| Tissue Specificity | Ubiquitously expressed, at various levels depending on the isoform and the tissue |
| Cellular Localization | Nucleus. Cytoplasm. |
| Entrez Gene | 11030 |
|---|
Application
RBPMS Antibody (C-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the RBPMS antibody detected the RBPMS protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
