Application
RDH12 antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the RDH12 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.Application
RDH12 Antibody (N-term) western blot analysis in mouse heart tissue and NIH-3T3 cell line lysates (35ug/lane).This demonstrates the RDH12 antibody detected the RDH12 protein (arrow).| Product Name | RDH12 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RDH12; Retinol dehydrogenase 12; All-trans and 9-cis retinol dehydrogenase |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| IHC:1:50~100 WB |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | RDH12 Retinol dehydrogenase 12 All-trans and 9-cis retinol dehydrogenase |
|---|---|
| Molecular Weight(MW) | 35094 Da |
| Function | Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase Displays high activity toward 9-cis and all-trans-retinol. Also involved in the metabolism of short-chain aldehydes. No steroid dehydrogenase activity detected. Might be the key enzyme in the formation of 11-cis-retinal from 11-cis-retinol during regeneration of the cone visual pigments |
| Tissue Specificity | Widely expressed, mostly in eye, kidney, brain, skeletal muscle and stomach |
| Entrez Gene | 145226 |
|---|---|
| Nucleotide Accession | NP_689656.2 |
Application
RDH12 antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the RDH12 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
RDH12 Antibody (N-term) western blot analysis in mouse heart tissue and NIH-3T3 cell line lysates (35ug/lane).This demonstrates the RDH12 antibody detected the RDH12 protein (arrow).| Application Notes | IHC:1:50~100 WB |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
