Application
RDH16 Antibody (N-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the RDH16 antibody detected the RDH16 protein (arrow).Application
RDH16 Antibody (N-term immunohistochemistry analysis in formalin fixed and paraffin embedded human skin carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the RDH16 Antibody (N-term for immunohistochemistry. Clinical relevance has not been evaluated.Application
RDH16 Antibody (N-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | RDH16 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RDH16; RODH4; Retinol dehydrogenase 16; Microsomal NAD(+)-dependent retinol dehydrogenase 4; Sterol/retinol dehydrogenase |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | RODH4 |
|---|---|
| Alternative Names | RDH16 RODH4 Retinol dehydrogenase 16 Microsomal NAD(+)-dependent retinol dehydrogenase 4 Sterol/retinol dehydrogenase |
| Molecular Weight(MW) | 35673 Da |
| Function | Oxidoreductase with a preference for NAD. Oxidizes all- trans-retinol and 13-cis-retinol to the corresponding aldehydes Has higher activity towards CRBP-bound retinol than with free retinol. Oxidizes 3-alpha-hydroxysteroids. Oxidizes androstanediol and androsterone to dihydrotestosterone and androstanedione. Can also catalyze the reverse reaction |
| Tissue Specificity | Highly expressed in adult liver (at protein level). Detected in endometrium, liver and foreskin. Detected in the spineous layers of adult skin, and at lower levels in basal and granular skin layers. Detected in fetal liver and lung |
| Cellular Localization | Microsome membrane; Single-pass type IV membrane protein. Endoplasmic reticulum membrane; Single-pass type IV membrane protein (Potential) |
| Entrez Gene | 8608 |
|---|---|
| Nucleotide Accession | NP_003699.3 |
Application
RDH16 Antibody (N-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the RDH16 antibody detected the RDH16 protein (arrow).
Application
RDH16 Antibody (N-term immunohistochemistry analysis in formalin fixed and paraffin embedded human skin carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the RDH16 Antibody (N-term for immunohistochemistry. Clinical relevance has not been evaluated.
Application
RDH16 Antibody (N-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
