Application
RENBP Antibody (C-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the RENBP antibody detected the RENBP protein (arrow).Application
RENBP Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RENBP Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.Application
RENBP Antibody (C-term) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.| Product Name | RENBP Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RENBP; N-acylglucosamine 2-epimerase; GlcNAc 2-epimerase; N-acetyl-D-glucosamine 2-epimerase; Renin-binding protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | RENBP N-acylglucosamine 2-epimerase GlcNAc 2-epimerase N-acetyl-D-glucosamine 2-epimerase Renin-binding protein |
|---|---|
| Molecular Weight(MW) | 48831 Da |
| Function | Catalyzes the interconversion of N-acetylglucosamine to N-acetylmannosamine. Binds to renin forming a protein complex called high molecular weight (HMW) renin and inhibits renin activity. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway: although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded |
| Tissue Specificity | This RENBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 327-357 amino acids from the C-terminal region of human RENBP. |
| Entrez Gene | 5973 |
|---|---|
| Nucleotide Accession | NP_002901.2 |
Application
RENBP Antibody (C-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the RENBP antibody detected the RENBP protein (arrow).
Application
RENBP Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RENBP Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
RENBP Antibody (C-term) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
