Application
RERG Antibody (N-term) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the RERG antibody detected the RERG protein (arrow).Application
RERG Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RERG Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | RERG Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RERG; Ras-related and estrogen-regulated growth inhibitor |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | RERG Ras-related and estrogen-regulated growth inhibitor |
|---|---|
| Molecular Weight(MW) | 22608 Da |
| Function | Binds GDP/GTP and possesses intrinsic GTPase activity. Has higher affinity for GDP than for GTP. In cell lines overexpression leads to a reduction in the rate of proliferation, colony formation and in tumorigenic potential |
| Tissue Specificity | Detected in heart, brain, placenta, lung, liver, skin, kidney and pancreas. Detected in estrogen receptor- positive breast-derived cell lines, but not in estrogen receptor- negative cell lines. Expression is decreased or lost in a significant proportion of primary breast tumors with poor clinical prognosis |
| Cellular Localization | Cytoplasm. |
| Entrez Gene | 85004 |
|---|---|
| Nucleotide Accession | NP_001177655.1 NP_116307.1 |
Application
RERG Antibody (N-term) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the RERG antibody detected the RERG protein (arrow).
Application
RERG Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RERG Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
