Application
RFFL Antibody (C-term) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the RFFL antibody detected the RFFL protein (arrow).| Product Name | RFFL (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | RNF189, RNF34L |
|---|---|
| Alternative Names | RFFL RNF189 RNF34L E3 ubiquitin-protein ligase rififylin Caspase regulator CARP2 Caspases-8 and -10-associated RING finger protein 2 FYVE-RING finger protein Sakura RING finger and FYVE-like domain-containing protein 1 RING finger protein 189 RING |
| Molecular Weight(MW) | 40514 Da |
| Function | Has E3 ubiquitin protein ligase activity. Regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. Has anti-apoptotic activity. May bind phosphatidylinositol phosphates |
| Tissue Specificity | Ubiquitous. Detected in spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocytes |
| Cellular Localization | Cytoplasm. Membrane; Peripheral membrane protein |
| Entrez Gene | 117584 |
|---|---|
| Nucleotide Accession | NP_476519.1 |
Application
RFFL Antibody (C-term) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the RFFL antibody detected the RFFL protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
