Application
Western blot analysis of anti-RGS19 Antibody (Y143) Pab pre-incubated without(lane 1) and with(lane 2) blocking peptide (BP1820e) in HL60 cell line lysate. RGS19(arrow) was detected using the purified Pab.Application
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with RGS19 Antibody (Y143) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.Application
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with RGS19 Antibody (Y143), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Product Name | RGS19 Antibody (Y143) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RGS19; GAIP; GNAI3IP; Regulator of G-protein signaling 19; G-alpha-interacting protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:50~100 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | GAIP GNAI3IP |
|---|---|
| Alternative Names | RGS19 GAIP GNAI3IP Regulator of G-protein signaling 19 G-alpha-interacting protein |
| Molecular Weight(MW) | 24636 Da |
| Function | Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2 Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein |
| Tissue Specificity | Highest expression in lung. Placenta, liver and heart also express high levels of GAIP |
| Cellular Localization | Membrane; Lipid-anchor. |
| Entrez Gene | 10287 |
|---|
Application
Western blot analysis of anti-RGS19 Antibody (Y143) Pab pre-incubated without(lane 1) and with(lane 2) blocking peptide (BP1820e) in HL60 cell line lysate. RGS19(arrow) was detected using the purified Pab.
Application
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with RGS19 Antibody (Y143) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Application
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with RGS19 Antibody (Y143), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Application Notes | WB:1:50~100 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
