Application
RGS2 Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the RGS2 antibody detected the RGS2 protein (arrow).| Product Name | RGS2 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RGS2; G0S8; Regulator of G-protein signaling 2; Cell growth-inhibiting gene 31 protein; G0/G1 switch regulatory protein 8 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | G0S8 |
|---|---|
| Alternative Names | RGS2 G0S8 Regulator of G-protein signaling 2 Cell growth-inhibiting gene 31 protein G0/G1 switch regulatory protein 8 |
| Molecular Weight(MW) | 24382 Da |
| Function | Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. May play a role in leukemogenesis Plays a role in negative feedback control pathway for adenylyl cyclase signaling. Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein |
| Tissue Specificity | Expressed in acute myelogenous leukemia (AML) and in acute lymphoblastic leukemia (ALL) |
| Cellular Localization | Isoform 1: Cell membrane. Cytoplasm. Nucleus, nucleolus Isoform 3: Cell membrane. Cytoplasm. Nucleus, nucleolus |
| Entrez Gene | 5997 |
|---|---|
| Nucleotide Accession | NP_002914.1 |
Application
RGS2 Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the RGS2 antibody detected the RGS2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Data sheet for OM219809