Application
RHOC Antibody (C-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the RHOC antibody detected the RHOC protein (arrow).Application
RHOC Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RHOC Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | RHOC Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ARH9, ARHC |
|---|---|
| Alternative Names | RHOC ARH9 ARHC Rho-related GTP-binding protein RhoC Rho cDNA clone 9 |
| Molecular Weight(MW) | 22006 Da |
| Function | Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Regulates apical junction formation in bronchial epithelial cells |
| Tissue Specificity | This RHOC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 101-130 amino acids from the C-terminal region of human RHOC. |
| Cellular Localization | Cell membrane; Lipid-anchor; Cytoplasmic side (Potential). Cleavage furrow. Note=Translocates to the equatorial region before furrow formation in a ECT2-dependent manner |
| Entrez Gene | 389 |
|---|---|
| Nucleotide Accession | NP_786886.1 NP_001036143.1 NP_001036144.1 |
Application
RHOC Antibody (C-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the RHOC antibody detected the RHOC protein (arrow).
Application
RHOC Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RHOC Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
