Application
RIC3 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RIC3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.Application
RIC3 Antibody (C-term) western blot analysis in NCI-H292,A549,WiDr,MDA-MB453 cell line lysates (35ug/lane).This demonstrates the RIC3 antibody detected the RIC3 protein (arrow).| Product Name | RIC3 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| IHC:1:10~50 WB |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | RIC3 Protein RIC-3 |
|---|---|
| Molecular Weight(MW) | 41092 Da |
| Function | Promotes functional expression of homomeric alpha-7 and alpha-8 nicotinic acetylcholine receptors at the cell surface. May also promote functional expression of homomeric serotoninergic 5- HT3 receptors, and of heteromeric acetylcholine receptors alpha- 3/beta-2, alpha-3/beta-4, alpha-4/beta-2 and alpha-4/beta-4 |
| Tissue Specificity | Broadly expressed, with high levels in muscle, brain, heart, pancreas and testis. In the central nervous system, highest levels are detected in the cerebellum and pituitary gland Over-expressed in brains from patients with bipolar disease or schizophrenia. Isoform 5 is predominantly expressed in the brain |
| Cellular Localization | Isoform 1: Endoplasmic reticulum membrane; Single-pass membrane protein |
| Entrez Gene | 79608 |
|---|---|
| Nucleotide Accession | NP_001128581.1 |
Application
RIC3 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RIC3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
RIC3 Antibody (C-term) western blot analysis in NCI-H292,A549,WiDr,MDA-MB453 cell line lysates (35ug/lane).This demonstrates the RIC3 antibody detected the RIC3 protein (arrow).| Application Notes | IHC:1:10~50 WB |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
