Application
The anti-RMP Pab is used in Western blot to detect RMP in T47D (left) and Jurkat (right) cell line lysates.| Product Name | RMP (URI) Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:250~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | C19orf2, NNX3, PPP1R19, RMP, URI |
|---|---|
| Alternative Names | URI1 C19orf2 NNX3 PPP1R19 RMP URI Unconventional prefoldin RPB5 interactor 1 Protein NNX3 Protein phosphatase 1 regulatory subunit 19 RNA polymerase II subunit 5-mediating protein |
| Molecular Weight(MW) | 59832 Da |
| Function | Involved in gene transcription regulation. Acts as a transcriptional repressor in concert with the corepressor UXT to regulate androgen receptor (AR) transcription. May act as a tumor suppressor to repress AR-mediated gene transcription and to inhibit anchorage-independent growth in prostate cancer cells Required for cell survival in ovarian cancer cells. Together with UXT, associates with chromatin to the NKX3-1 promoter region Antagonizes transcriptional modulation via hepatitis B virus X protein |
| Tissue Specificity | Ubiquitous. Expressed in ovarian cancers (at protein level). Expressed strongly in skeletal muscle. Expressed weakly in brain, heart, pancreas and in prostate epithelial cells |
| Cellular Localization | Nucleus. Cytoplasm. Mitochondrion. Cell projection, dendrite (By similarity). Note=Colocalizes with PFDN2, PFDN4, PPP1CC, RPS6KB1 and STAP1 at mitochondrion |
| Entrez Gene | 8725 |
|---|
Application
The anti-RMP Pab is used in Western blot to detect RMP in T47D (left) and Jurkat (right) cell line lysates.| Application Notes | WB:1:250~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
