Application
Western blot analysis of RNASEH2B Antibody (Center) in CEM cell line lysates (35ug/lane). RNASEH2B (arrow) was detected using the purified Pab.Application
RNASEH2B Antibody (Center) IHC analysis in formalin fixed and paraffin embedded human lymph tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the RNASEH2B Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | RNASEH2B Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RNASEH2B; DLEU8; Ribonuclease H2 subunit B; Aicardi-Goutieres syndrome 2 protein; Deleted in lymphocytic leukemia 8; Ribonuclease HI subunit B |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | DLEU8 |
|---|---|
| Alternative Names | RNASEH2B DLEU8 Ribonuclease H2 subunit B Aicardi-Goutieres syndrome 2 protein Deleted in lymphocytic leukemia 8 Ribonuclease HI subunit B |
| Molecular Weight(MW) | 35139 Da |
| Function | Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging- strand Okazaki fragment RNA primers during DNA replication Mediates the excision of single ribonucleotides from DNA:RNA duplexes |
| Tissue Specificity | Widely expressed. |
| Cellular Localization | Nucleus (Probable). |
| Entrez Gene | 79621 |
|---|
Application
Western blot analysis of RNASEH2B Antibody (Center) in CEM cell line lysates (35ug/lane). RNASEH2B (arrow) was detected using the purified Pab.
Application
RNASEH2B Antibody (Center) IHC analysis in formalin fixed and paraffin embedded human lymph tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the RNASEH2B Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
