Application
RNF128 Antibody (Center) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the RNF128 antibody detected the RNF128 protein (arrow).| Product Name | RNF128 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RNF128; GRAIL; E3 ubiquitin-protein ligase RNF128; Gene related to anergy in lymphocytes protein; RING finger protein 128 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | GRAIL |
|---|---|
| Alternative Names | RNF128 GRAIL E3 ubiquitin-protein ligase RNF128 Gene related to anergy in lymphocytes protein RING finger protein 128 |
| Molecular Weight(MW) | 46521 Da |
| Function | E3 ubiquitin-protein ligase that catalyzes polyubiquitin chains. Functions as an inhibitor of cytokine gene transcription Inhibits IL2 and IL4 transcription and this activity is likely to be mediated by E3 ligase activity. Plays an important role in the induction of the anergic phenotype. Functions in the patterning of the dorsal ectoderm; sensitizes ectoderm to respond to neural- inducing signals (By similarity) |
| Tissue Specificity | This RNF128 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-143 amino acids from the Central region of human RNF128. |
| Cellular Localization | Endomembrane system; Single-pass membrane protein (By similarity). Cytoplasm, perinuclear region (By similarity). Note=Localized in an asymmetric perinuclear punctate manner. Localizes to the internal pool of the transferrin recycling endosomal pathway. Partially colocalized with the endoplasmic reticulum resident HSPA5, with Golgi resident STX5, and with the late endosomal GTPase RAB7A (By similarity) |
| Entrez Gene | 79589 |
|---|---|
| Nucleotide Accession | NP_078815.3 |
Application
RNF128 Antibody (Center) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the RNF128 antibody detected the RNF128 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
