Application
RNF135 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the RNF135 antibody detected the RNF135 protein (arrow).| Product Name | RNF135 (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RNF135; E3 ubiquitin-protein ligase RNF135; RIG-I E3 ubiquitin ligase; RING finger protein 135; Riplet |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | RNF135 E3 ubiquitin-protein ligase RNF135 RIG-I E3 ubiquitin ligase RING finger protein 135 Riplet |
|---|---|
| Molecular Weight(MW) | 47888 Da |
| Function | Acts as an E2-dependent E3 ubiquitin-protein ligase, involved in innate immune defense against viruses. Ubiquitinates DDX58 and is required for full activation of the DDX58 signaling resulting in interferon beta production |
| Tissue Specificity | Expressed in skeletal muscle, spleen, kidney, placenta, prostate, stomach, thyroid and tongue. Also weakly expressed in heart, thymus, liver and lung |
| Cellular Localization | Cytoplasm. |
| Entrez Gene | 84282 |
|---|---|
| Nucleotide Accession | NP_115698.3 |
Application
RNF135 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the RNF135 antibody detected the RNF135 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
