Application
RNF19B Antibody (Center) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the RNF19B antibody detected the RNF19B protein (arrow).Application
RNF19B Antibody (Center) flow cytometric analysis of MCF-7 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | RNF19B Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBFC |
| WB:1:100~500 FC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | IBRDC3, NKLAM |
|---|---|
| Alternative Names | RNF19B IBRDC3 NKLAM E3 ubiquitin-protein ligase RNF19B IBR domain-containing protein 3 Natural killer lytic-associated molecule RING finger protein 19B |
| Molecular Weight(MW) | 77925 Da |
| Function | E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as UCKL1. Involved in the cytolytic activity of natural killer cells and cytotoxic T-cells |
| Tissue Specificity | Expressed specifically in natural killer cells, activated macrophages and cytotoxic T-cells. Present in natural killer cells (at protein level) |
| Cellular Localization | Cytoplasmic granule membrane; Multi-pass membrane protein |
| Entrez Gene | 127544 |
|---|---|
| Nucleotide Accession | NP_001120833.1 NP_699172.2 |
Application
RNF19B Antibody (Center) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the RNF19B antibody detected the RNF19B protein (arrow).
Application
RNF19B Antibody (Center) flow cytometric analysis of MCF-7 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 FC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
