RNF182 Antibody (N-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the RNF182 antibody detected the RNF182 protein (arrow).
RNF182; E3 ubiquitin-protein ligase RNF182; RING finger protein 182
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Alternative Names
RNF182 E3 ubiquitin-protein ligase RNF182 RING finger protein 182
Molecular Weight(MW)
27402 Da
Function
E3 ubiquitin-protein ligase that mediates the ubiquitination of ATP6V0C and targets it to degradation via the ubiquitin-proteasome pathway
Tissue Specificity
Up-regulated in neuronal cells subjected to cell death-inducing injuries, such as oxygen and glucose deprivation (at protein level). Could be up-regulated in Alzheimer disease brains
Cellular Localization
Membrane; Multi-pass membrane protein (Potential). Cytoplasm
RNF182 Antibody (N-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the RNF182 antibody detected the RNF182 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.