RNF34 Antibody (C-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the RNF34 antibody detected the RNF34 protein (arrow).
RNF34 E3 ubiquitin-protein ligase RNF34 Caspase regulator CARP1 Caspases-8 and -10-associated RING finger protein 1 FYVE-RING finger protein Momo Human RING finger homologous to inhibitor of apoptosis protein RING finger protein 34 RING finger prote
Molecular Weight(MW)
41641 Da
Function
Has E3 ubiquitin-protein ligase activity. Regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. Protects cells against apoptosis induced by TNF Binds phosphatidylinositol 5-phosphate and phosphatidylinositol 3- phosphate
Tissue Specificity
Ubiquitous. Detected in heart, brain, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, colon and leukocytes
Cellular Localization
Nucleus speckle. Endomembrane system; Peripheral membrane protein
RNF34 Antibody (C-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the RNF34 antibody detected the RNF34 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.