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RNT2 Antibody (N-term)

Catalog Number:OM220054
OM220054
Discount Price
OM220054-100ul
1~2 Week
100ul
OM220054-50ul
50ul
OM220054-20ul
20ul
1~2 Week
Product Profile
Product Name RNT2 Antibody (N-term)
Antibody Type Primary Antibodies
Antigen Alias RNASET2; RNASE6PL; Ribonuclease T2; Ribonuclease 6
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms RNASE6PL
Alternative Names RNASET2
RNASE6PL
Ribonuclease T2
Ribonuclease 6
Molecular Weight(MW) 29481 Da
Function Has ribonuclease activity, with higher activity at acidic pH. Probably is involved in lysosomal degradation of ribosomal RNA (By similarity). Probably plays a role in cellular RNA catabolism
Tissue Specificity Ubiquitous. Higher expression levels observed in the temporal lobe and fetal brain
Cellular Localization Secreted. Lysosome lumen. Endoplasmic reticulum lumen. Note=Subcellular fractionation of transfected ovarian cancer cells reveals full-length RNASET2 in the endoplasmic reticulum fraction and the 2 smaller RNASET2 proteolytic products in the lysosome fraction
Database Links
Entrez Gene 8635
Nucleotide Accession NP_003721.2
Application

Application

RNT2 Antibody (N-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the RNT2 antibody detected the RNT2 protein (arrow).

Application

RNT2 antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human spleen carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the RNT2 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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