Application
RORC Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the RORC antibody detected the RORC protein (arrow).| Product Name | RORC Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RORC; NR1F3; RORG; RZRG; Nuclear receptor ROR-gamma; Nuclear receptor RZR-gamma; Nuclear receptor subfamily 1 group F member 3; Retinoid-related orphan receptor-gamma |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | NR1F3 RORG RZRG |
|---|---|
| Alternative Names | RORC NR1F3 RORG RZRG Nuclear receptor ROR-gamma Nuclear receptor RZR-gamma Nuclear receptor subfamily 1 group F member 3 Retinoid-related orphan receptor-gamma |
| Molecular Weight(MW) | 58195 Da |
| Function | Possible nuclear receptor for hydroxycholesterols, the binding of which strongly promotes coactivators recruitment Essential for thymopoiesis and the development of several secondary lymphoid tissues, including lymph nodes. Involved in lineage specification of uncommitted CD4(+) T-helper cells into Th17 cells. Regulate the expression of several components of the circadian clock |
| Tissue Specificity | Isoform 1 is widely expressed in many tissues, including liver and adipose, and highly expressed in skeletal muscle. Isoform 2 is primarily expressed in immature thymocytes |
| Cellular Localization | Nucleus (Probable). |
| Entrez Gene | 6097 |
|---|---|
| Nucleotide Accession | NP_001001523.1 NP_005051.2 |
Application
RORC Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the RORC antibody detected the RORC protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
