Application
RPA4 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the RPA4 antibody detected the RPA4 protein (arrow).| Product Name | RPA4 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RPA4; Replication protein A 30 kDa subunit; Replication factor A protein 4 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | RPA4 Replication protein A 30 kDa subunit Replication factor A protein 4 |
|---|---|
| Molecular Weight(MW) | 28868 Da |
| Function | Functions as component of the alternative replication protein A complex (aRPA). aRPA binds single-stranded DNA and probably plays a role in DNA repair; it does not support chromosomal DNA replication and cell cycle progression through S- phase. In vitro, aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange |
| Tissue Specificity | Preferentially expressed in placental and colon mucosa. Widely expressed at intermediate or lower levels |
| Cellular Localization | Nucleus. Note=Localizes to DNA repair foci after DNA damage |
| Entrez Gene | 29935 |
|---|---|
| Nucleotide Accession | NP_037479.1 |
Application
RPA4 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the RPA4 antibody detected the RPA4 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
