Application
RPGR Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the RPGR antibody detected the RPGR protein (arrow).Application
RPGR Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RPGR Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | RPGR Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RPGR; RP3; XLRP3; X-linked retinitis pigmentosa GTPase regulator |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | RP3 XLRP3 |
|---|---|
| Alternative Names | RPGR RP3 XLRP3 X-linked retinitis pigmentosa GTPase regulator |
| Molecular Weight(MW) | 113387 Da |
| Function | Could be a guanine-nucleotide releasing factor. Plays a role in ciliogenesis. Probably regulates cilia formation by regulating actin stress filaments and cell contractility. Plays an important role in photoreceptor integrity. May play a critical role in spermatogenesis and in intraflagellar transport processes (By similarity). May be involved in microtubule organization and regulation of transport in primary cilia |
| Tissue Specificity | Heart, brain, placenta, lung, liver, muscle, kidney, retina, pancreas and fetal retinal pigment epithelium Isoform 3 is found only in the retina. Colocalizes with RPGRIP1 in the outer segment of rod photoreceptors and cone outer segments |
| Cellular Localization | Cytoplasm, cytoskeleton, flagellum axoneme (By similarity). Golgi apparatus |
| Entrez Gene | 6103 |
|---|---|
| Nucleotide Accession | NP_000319.1 |
Application
RPGR Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the RPGR antibody detected the RPGR protein (arrow).
Application
RPGR Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RPGR Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
