Application
RRAGC Antibody (Center) western blot analysis in 293,MDA-MB231,Hela,HepG2 cell line lysates (35ug/lane).This demonstrates the RRAGC antibody detected the RRAGC protein (arrow).Application
RRAGC Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RRAGC Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | RRAGC Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | RRAGC Ras-related GTP-binding protein C GTPase-interacting protein 2 TIB929 |
|---|---|
| Molecular Weight(MW) | 44224 Da |
| Function | Has guanine nucleotide-binding activity but weak intrinsic GTPase activity. Probably required for the amino acid- induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids |
| Tissue Specificity | This RRAGC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-198 amino acids from the Central region of human RRAGC. |
| Cellular Localization | Cytoplasm. Nucleus. Lysosome. Note=Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state of associated RRAGA |
| Entrez Gene | 64121 |
|---|---|
| Nucleotide Accession | NP_071440.1 |
Application
RRAGC Antibody (Center) western blot analysis in 293,MDA-MB231,Hela,HepG2 cell line lysates (35ug/lane).This demonstrates the RRAGC antibody detected the RRAGC protein (arrow).
Application
RRAGC Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RRAGC Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
