Application
RRAGB Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the RRAGB antibody detected the RRAGB protein (arrow).| Product Name | RRAGB Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RRAGB; Ras-related GTP-binding protein B |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | RRAGB Ras-related GTP-binding protein B |
|---|---|
| Molecular Weight(MW) | 43250 Da |
| Function | Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity. Required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. Involved in the RCC1/Ran-GTPase pathway |
| Tissue Specificity | This RRAGB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human RRAGB. |
| Cellular Localization | Cytoplasm. Lysosome. |
| Entrez Gene | 10325 |
|---|---|
| Nucleotide Accession | NP_006055.3 |
Application
RRAGB Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the RRAGB antibody detected the RRAGB protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
