RPS6KA2, RSK3, Ribosomal protein S6 kinase alpha-2, pp90RSK3;MAP kinase-activated protein kinase 1c
Key Feature
Clonality
Monoclonal
Clone Number
E202
Host Species
Rabbit
Tested Applications
IHCWB
IHC:1:50~1:100 WB
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
MAPKAPK1C RSK3
Alternative Names
RPS6KA2 RSK3 Ribosomal protein S6 kinase alpha-2 pp90RSK3 MAP kinase-activated protein kinase 1c
Molecular Weight(MW)
83239 Da
Function
Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of transcription factors, regulates translation, and mediates cellular proliferation, survival, and differentiation. May function as tumor suppressor in epithelial ovarian cancer cells
Tissue Specificity
Widely expressed with higher expression in lung, skeletal muscle, brain, uterus, ovary, thyroid and prostate