Application
RTN4R Antibody (Center) western blot analysis in Y79 cell line lysates (35ug/lane).This demonstrates the RTN4R antibody detected the RTN4R protein (arrow).Application
RTN4R Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RTN4R Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | RTN4R Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RTN4R; NOGOR; Reticulon-4 receptor; Nogo receptor; Nogo-66 receptor |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | NOGOR |
|---|---|
| Alternative Names | RTN4R NOGOR Reticulon-4 receptor Nogo receptor Nogo-66 receptor |
| Molecular Weight(MW) | 50708 Da |
| Function | Receptor for RTN4, OMG and MAG. Mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. Acts in conjunction with RTN4 and LIGO1 in regulating neuronal precursor cell motility during cortical development (By similarity) |
| Tissue Specificity | Widespread in the brain but highest levels in the gray matter. Low levels in heart and kidney not expressed in oligodendrocytes (white matter) |
| Cellular Localization | Cell membrane; Lipid-anchor, GPI-anchor. |
| Entrez Gene | 65078 |
|---|---|
| Nucleotide Accession | NP_075380.1 |
Application
RTN4R Antibody (Center) western blot analysis in Y79 cell line lysates (35ug/lane).This demonstrates the RTN4R antibody detected the RTN4R protein (arrow).
Application
RTN4R Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RTN4R Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
