Application
RYBP Antibody (N-term) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the RYBP antibody detected the RYBP protein (arrow).Application
Western blot analysis of RYBP (arrow) using rabbit polyclonal RYBP Antibody (N-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the RYBP gene.| Product Name | RYBP Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RYBP; DEDAF; YEAF1; RING1 and YY1-binding protein; Apoptin-associating protein 1; Death effector domain-associated factor; YY1 and E4TF1-associated factor 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | DEDAF YEAF1 |
|---|---|
| Alternative Names | RYBP DEDAF YEAF1 RING1 and YY1-binding protein Apoptin-associating protein 1 Death effector domain-associated factor YY1 and E4TF1-associated factor 1 |
| Molecular Weight(MW) | 24822 Da |
| Function | Inhibits ubiquitination and subsequent degradation of TP53, and thereby plays a role in regulating transcription of TP53 target genes. May be implicated in the regulation of the transcription as a repressor of the transcriptional activity of E4TF1. May bind to DNA. Promotes apoptosis |
| Tissue Specificity | Widely expressed with highest levels in lymphoid tissues and placenta |
| Cellular Localization | Nucleus. Cytoplasm. Nucleus, nucleoplasm (By similarity). Note=Primarily found in the nucleus. Detected in a punctate pattern likely to represent Polycomb group (PcG) bodies (By similarity) |
| Entrez Gene | 23429 |
|---|---|
| Nucleotide Accession | NP_036366.3 |
Application
RYBP Antibody (N-term) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the RYBP antibody detected the RYBP protein (arrow).
Application
Western blot analysis of RYBP (arrow) using rabbit polyclonal RYBP Antibody (N-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the RYBP gene.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
