Application
B. Immunohistochemical analysis of paraffin-embedded human melanoma using anti- S100-beta RabMAb (Cat. #AJ1702a).Application
A. Western blot analysis on A375 cell lysate using anti- S100-beta RabMAb (Cat. #AJ1702a), dilution 1:1000.| Product Name | S100 beta Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | S100B, Protein S100-B, S100 calcium-binding protein B;S-100 protein subunit beta;S-100 protein beta chain |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EP1576Y |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| IHC:1:250~500 WB |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | S100B Protein S100-B S100 calcium-binding protein B S-100 protein subunit beta S-100 protein beta chain |
|---|---|
| Molecular Weight(MW) | 10713 Da |
| Function | Weakly binds calcium but binds zinc very tightly- distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling (By similarity). Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization |
| Tissue Specificity | Although predominant among the water-soluble brain proteins, S100 is also found in a variety of other tissues |
| Cellular Localization | Cytoplasm. Nucleus. |
| Entrez Gene | 6285 |
|---|
Application
B. Immunohistochemical analysis of paraffin-embedded human melanoma using anti- S100-beta RabMAb (Cat. #AJ1702a).
Application
A. Western blot analysis on A375 cell lysate using anti- S100-beta RabMAb (Cat. #AJ1702a), dilution 1:1000.| Application Notes | IHC:1:250~500 WB |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
