Application
S100B/S-100 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the S100B/S-100 antibody detected the S100B/S-100 protein (arrow).| Product Name | S100B/S-100 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | S100B; Protein S100-B; S-100 protein beta chain; S-100 protein subunit beta; S100 calcium-binding protein B |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | S100B Protein S100-B S-100 protein beta chain S-100 protein subunit beta S100 calcium-binding protein B |
|---|---|
| Molecular Weight(MW) | 10713 Da |
| Function | Weakly binds calcium but binds zinc very tightly- distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling (By similarity). Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization |
| Tissue Specificity | Although predominant among the water-soluble brain proteins, S100 is also found in a variety of other tissues |
| Cellular Localization | Cytoplasm. Nucleus. |
| Entrez Gene | 6285 |
|---|---|
| Nucleotide Accession | NP_006263.1 |
Application
S100B/S-100 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the S100B/S-100 antibody detected the S100B/S-100 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
