S47A2 Antibody (N-term) western blot analysis in mouse kidney tissue and A2058 cell line lysates (35ug/lane).This demonstrates the S47A2 antibody detected the S47A2 protein (arrow).
SLC47A2; MATE2; Multidrug and toxin extrusion protein 2; Kidney-specific H(+)/organic cation antiporter; Solute carrier family 47 member 2
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
MATE2
Alternative Names
SLC47A2 MATE2 Multidrug and toxin extrusion protein 2 Kidney-specific H(+)/organic cation antiporter Solute carrier family 47 member 2
Molecular Weight(MW)
65085 Da
Function
Solute transporter for tetraethylammonium (TEA), 1- methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide, metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, and ganciclovir. Responsible for the secretion of cationic drugs across the brush border membranes
Tissue Specificity
Isoform 3 is predominantly expressed in kidney. Isoform 6 is expressed in brain
Cellular Localization
Cell membrane; Multi-pass membrane protein (Potential). Note=Localized at the brush border membranes of the proximal tubules
S47A2 Antibody (N-term) western blot analysis in mouse kidney tissue and A2058 cell line lysates (35ug/lane).This demonstrates the S47A2 antibody detected the S47A2 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.