Application
SAFB Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the SAFB antibody detected the SAFB protein (arrow).| Product Name | SAFB Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SAFB; HET; HAP; SAFB1; Scaffold attachment factor B1; HSP27 estrogen response element-TATA box-binding protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | HAP HET SAFB1 |
|---|---|
| Alternative Names | SAFB HET HAP SAFB1 Scaffold attachment factor B1 HSP27 estrogen response element-TATA box-binding protein |
| Molecular Weight(MW) | 102642 Da |
| Function | Binds to scaffold/matrix attachment region (S/MAR) DNA and forms a molecular assembly point to allow the formation of a 'transcriptosomal' complex (consisting of SR proteins and RNA polymerase II) coupling transcription and RNA processing (By similarity). Can function as an estrogen receptor corepressor and can also bind to the HSP27 promoter and decrease its transcription. When associated with RBMX, binds to and stimulates transcription from the SREBF1 promoter (By similarity). Can inhibit cell proliferation |
| Tissue Specificity | Ubiquitous. Expressed at high levels in the CNS and at low levels in the liver. Expressed in a wide number of breast cancer cell lines |
| Cellular Localization | Nucleus. |
| Entrez Gene | 6294 |
|---|---|
| Nucleotide Accession | NP_002958.2 |
Application
SAFB Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the SAFB antibody detected the SAFB protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
