Application
A.Western blot analysis on (A) HeLa and (B) Jurkat cell lysates using anti- SAM68 RabMAb (Cat. #AJ1704a), dilution 1:100,000.Application
B.Immunohistochemivcal analysis of paraffin-embedded human brain tissue using anti- SAM68 RabMAb (Cat. #AJ1704a).Application
C.Immunofluorescent staining of HeLa cells using anti-SAM 68 RaMAb (Cat. #AJ1704a).| Product Name | SAM68 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CTNND1, KIAA0384, Catenin delta-1, p120(cas) |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EPR3231 |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:20000~50000 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | SAM68 |
|---|---|
| Alternative Names | CTNND1 KIAA0384 Catenin delta-1 p120(cas) |
| Molecular Weight(MW) | 48227 Da |
| Function | Recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain- containing proteins. Role in G2-M progression in the cell cycle Represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. Also acts as a putative regulator of mRNA stability and/or translation rates and mediates mRNA nuclear export |
| Tissue Specificity | Ubiquitously expressed in all tissue examined. Isoform 1 is expressed at lower levels in brain, skeletal muscle, and liver whereas isoform 3 is intensified in skeletal muscle and in liver |
| Cellular Localization | Nucleus. Membrane. |
| Entrez Gene | 10657 |
|---|
Application
A.Western blot analysis on (A) HeLa and (B) Jurkat cell lysates using anti- SAM68 RabMAb (Cat. #AJ1704a), dilution 1:100,000.
Application
B.Immunohistochemivcal analysis of paraffin-embedded human brain tissue using anti- SAM68 RabMAb (Cat. #AJ1704a).
Application
C.Immunofluorescent staining of HeLa cells using anti-SAM 68 RaMAb (Cat. #AJ1704a).| Application Notes | WB:1:20000~50000 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
