Application
SAP18 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the SAP18 antibody detected the SAP18 protein (arrow).| Product Name | SAP18 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SAP18; Histone deacetylase complex subunit SAP18; 18 kDa Sin3-associated polypeptide; 2HOR0202; Cell growth-inhibiting gene 38 protein; Sin3-associated polypeptide p18 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | SAP18 Histone deacetylase complex subunit SAP18 18 kDa Sin3-associated polypeptide 2HOR0202 Cell growth-inhibiting gene 38 protein Sin3-associated polypeptide p18 |
|---|---|
| Molecular Weight(MW) | 17561 Da |
| Function | Component of the SIN3-repressing complex. Enhances the ability of SIN3-HDAC1-mediated transcriptional repression. When tethered to the promoter, it can direct the formation of a repressive complex to core histone proteins. Component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism |
| Tissue Specificity | Ubiquitous. |
| Cellular Localization | Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm |
| Entrez Gene | 10284 |
|---|---|
| Nucleotide Accession | NP_005861.2 |
Application
SAP18 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the SAP18 antibody detected the SAP18 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
