Application
SCAR5 Antibody (C-term) western blot analysis in mouse heart tissue lysates (15ug/lane).This demonstrates the SCAR5 antibody detected SCAR5 protein (arrow).Application
SCAR5 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SCAR5 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | SCAR5 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SCARA5; Scavenger receptor class A member 5; Scavenger receptor hlg |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | SCARA5 Scavenger receptor class A member 5 Scavenger receptor hlg |
|---|---|
| Molecular Weight(MW) | 53994 Da |
| Function | Ferritin receptor that mediates non-transferrin- dependent delivery of iron. Mediates cellular uptake of ferritin- bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type- specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1) (By similarity) |
| Tissue Specificity | This SCAR5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 392-421 amino acids from the C-terminal region of human SCAR5. |
| Cellular Localization | Cell membrane; Single-pass type II membrane protein (By similarity) |
| Entrez Gene | 286133 |
|---|---|
| Nucleotide Accession | NP_776194.2 |
Application
SCAR5 Antibody (C-term) western blot analysis in mouse heart tissue lysates (15ug/lane).This demonstrates the SCAR5 antibody detected SCAR5 protein (arrow).
Application
SCAR5 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SCAR5 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
